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Symbol Name ID |
Cdk4
cyclin dependent kinase 4 MGI:88357 |
| Darker colors indicate more annotations |
| Human Phenotypes | Prostate cancer |
| Disease(s) Associated with CDK4 | |
| prostate cancer |
| Mouse Phenotypes | azoospermia |
oligozoospermia |
abnormal corpus luteum morphology |
small ovary |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
abnormal Sertoli cell morphology |
small seminiferous tubules |
decreased Leydig cell number |
absent Leydig cells |
increased Leydig cell number |
decreased testis weight |
small testis |
abnormal female reproductive system morphology |
abnormal male reproductive system morphology |
abnormal female reproductive system physiology |
delayed estrus |
impaired luteinization |
female infertility |
abnormal fertility/fecundity |
male infertility |
reduced male fertility |
abnormal male reproductive system physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Cdk4tm1.1Bbd/Cdk4tm1.1Bbd | ||||||||||||||||||||||||
| Cdk4tm1b(NCOM)Mfgc/Cdk4tm1b(NCOM)Mfgc | ||||||||||||||||||||||||
| Cdk4tm1Bbd/Cdk4tm1Bbd | ||||||||||||||||||||||||
| Cdk4tm1Kiyo/Cdk4tm1Kiyo | ||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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